Kuster, and A. Wobus, "Non-thermal effects of power-line magnetic fields 50 Hz on gene expression levels of pluripotent embryonic stem cells-the role of tumour suppressor p53," Mutat. Simko, M. Mattsson, "Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: Possible immune cell activation," J. Cell Biochem.
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Frahm, J. Lantow, M. Lupke, D. Weiss, and M. Simko, "Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields," J. Villarini, M. Moretti, G. Scassellati-Sforzolini, B. Boccioli, and R.
Pasquini, "Effects of co-exposure to extremely low frequency 50 Hz magnetic fields and xenobiotics determined in vitro by the alkaline comet assay," Sci. Total Environ. Stronati, L. Testa, P. Villani, C. Marino, G. Lovisolo, D. Conti, F.
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Russo, A. Fresegna, and E. Cordelli, "Absence of genotoxicity in human blood cells exposed to 50 Hz magnetic fields as assessed by comet assay, chromosome aberration, micronucleus, and sister chromatid exchange analyses," Bioelectromagnetics , Vol. Canbay, C. Greene, L. Tischler, "Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor," Proceedings of the National Academy of Sciences of the United States of America , Vol.
Mazzoleni, T. Pietrangelo, S. Guarnieri, C. Morabito, N. Steimberg, and G. Yaffe, D. Saxel, "Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle," Nature , Vol. Iezzi, M. Felicetti, L. Borgia, T. Pannellini, G. Mariggio, A. Pietrangelo, A. Mezzetti, F. Lap 3 catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Other proteins had similar expressions between control and 1 mT after 4 weeks, including Vdac1.
It has been reported that normal mitochondrial permeability is essential for learning and memory tasks, in which related proteins VDAC isoform as proteins in the mitochondrial outer membrane permeability that increment leads to developmental abnormalities in neuronal architecture. Herein the down-regulation of VDAC1 after 2 week and up-regulation after 4 weeks might be linked to altered short-term memory and adaptation. Tppp, tubulin polymerization promoting protein, had a decreased rate in time by 1mT, and may play a role in the polymerization ultrastructure, thus maintaining the integrity of the microtubule network in the brain.
TPPP is involved in the normal functions of key proteins i. PrP and play a role as protective factors for cells against the damage effects of the accumulation of abnormal forms 24 , This protein is directly linked to memory associated hippocampus structure, thus decreasing memory in the exposure radiation might be related to down regulated Tppp expression. VDAC and Tppp rely on cell adaptation in exposure radiation. Network analysis emphasizes the crucial function of these proteins in the brain because structural analysis determined that all these proteins are hub.
Gene ontology analysis also determined the functions of these proteins were related to two important brain functions, including cytoskeletal neurons and metabolic processes. These processes were related to short memory formation in the hippocampus so the molecular deficiency in this part of the brain led to a neuronal disorder, such as a neurodegenerative disease 35 , In conclusion, the result of our previous study on behavioral changes decreased memory and movement defects affected by increased intensity of ELF-EMF and the findings of the current study showed that adaptation timing in molecular levels were related to down-regulation in critical hippocampus protein expressions, most of which belonged to cytoskeletal processes.
Therefore, a disorder in behavioral tests might be linked to disarrangement in hippocampus cell structures. Potential health impacts of residential exposures to extremely low frequency magnetic fields in Europe. Environ Int. Karasek M, Woldanska-Okonska M. Electromagnetic fields and human endocrine system. Induction of DNA strand breaks by intermittent exposure to extremely-low-frequency electromagnetic fields in human diploid fibroblasts. Mutat Res. Exp Neurol. Proteomics study of extremely low frequency electromagnetic field, 50 Hz on human neuroblastoma cells.
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Proteomic analysis in human fibroblasts by continuous exposure to extremely low-frequency electromagnetic fields. Pak J Biol Sci. Pooled analysis of recent studies on magnetic fields and childhood leukaemia. Br J Cancer. Schuz J. Exposure to extremely low-frequency magnetic fields and the risk of childhood cancer: update of the epidemiological evidence.
Prog Biophys Mol Biol. Pilot study of extremely low frequency magnetic fields emitted by transformers in dwellings. Social aspects. Electromagn Biol Med. Biochim Biophys Acta. Fifty hertz extremely low-frequency electromagnetic field causes changes in redox and differentiative status in neuroblastoma cells. Int J Biochem Cell Biol. Proliferation and differentiation of rat bone marrow stem cells by muT electromagnetic field. Neurosci Lett. Extremely low-frequency electromagnetic fields promote in vitro neurogenesis via upregulation of Ca v 1-channel activity.
J Cell Physiol. Singh N, Lai H. Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields.
Scientific studies on EMFs - Powerwatch
Neuronal cellular responses to extremely low frequency electromagnetic field exposure: implications regarding oxidative stress and neurodegeneration. PLoS One. Power frequency magnetic field exposure and gap junctional communication in Clone 9 cells. Extremely low frequency electromagnetic field enhances human keratinocyte cell growth and decreases proinflammatory chemokine production.
Br J Dermatol. Toxicol Lett. Guidelines for limiting exposure to time-varying electric and magnetic fields 1 Hz to kHz.
Biological Effects of Electric and Magnetic Fields
Health Phys. Govindaraj V, Rao AJ. Proteomic identification of non-erythrocytic alpha-spectrin-1 down-regulation in the pre-optic area of neonatally estradiolbeta treated female adult rats. Steimberg, and G. Yaffe, D. Saxel, "Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle," Nature , Vol.
Iezzi, M. Felicetti, L. Borgia, T. Pannellini, G. Mariggio, A. Pietrangelo, A. Mezzetti, F. Cuccurullo, and P. Falone, S. Cellini, L. Di Loreto, S. Anand, N. Stead, "Neuron-specific enolase as a marker for acute ischemic stroke: A systematic review," Cerebrovasc Dis. Pietrangelo, T. Ross, S. Van Den Heuvel, R. Leppens, G. Nemethova, and L. Verschaeve, "Haemopoietic cell proliferation in murine bone marrow cells exposed to extreme low frequency ELF electromagnetic fields," Toxicol in Vitro , Vol.
Electromagnetic radiation and health
Wolf, F. Regoli, F. Gorbi, N. Machella, S. Tedesco, M. Benedetti, R. Bocchetti, A. Notti, D. Fattorini, F. Piva, and G. Principato, "Pro-oxidant effects of extremely low frequency electromagnetic fields in the land snail Helix aspersa," Free Radic. Harakawa, S.
go Inoue, T. Hori, K. Tochio, T. Kariya, K. Takahashi, F. Doge, H. Suzuki, and H. Nagasawa, "Effects of a 50 Hz electric field on plasma lipid peroxide level and antioxidant activity in rats," Bioelectromagnetics , Vol.